Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse?

Allogeneic hematopoietic cell transplantation provides effective control of hematopoietic malignancies, but with an associated risk of graft-versus-host disease (GVHD) related morbidity and mortality.Several advances in hematopoietic cell transplantation including high resolution HLA typing, development of Playskool building toys reduced intensity

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Activities organised for the illegal trafficking of waste and living law: is it still relevant and reasonable to include the offences referred to in article 51, paragraph 3 bis of the code of criminal procedure?

he case law shows that the offence provided by Art.452 quaterdecies of the criminal code is widely applied to misconducts which are not Playskool building toys connected to contexts of organized crime.This structure of the "living law" makes unreasonable the current inclusion of the crime, (as an autonomous Denim offence, and not as an offence for

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Dynamic order Markov model for categorical sequence clustering

Abstract Markov models are extensively used for categorical sequence clustering and classification due to their inherent ability to capture complex chronological dependencies hidden in sequential data.Existing Markov Moisturizer models are based on an implicit assumption that the probability of the next state depends on the preceding context/patter

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